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Low intensity radiofrequency radiation: a new oxidant for living cells
Ukraine Created: 21 Apr 2014
Radiofrequency radiation (RFR), electromagnetic waves emitted by our cell phones and Wi-Fi, are referred to as non-ionizing. This means that in contrast to the ionizing radiation, which does induce ionization of water and biologically important macromolecules,

RFR does not have a capacity for such effects. Unlike, for example X-rays, the energy of RFR is not enough to break electrons off the molecules. However, is RFR completely safe for public health? Traditionally, the industry and the public bodies said yes. Nevertheless, new research data change this perception.

Oxidative stress is an induced imbalance between pro-oxidant and antioxidant systems resulting in oxidative damage to proteins, lipids and DNA; and is closely connected to overproduction of reactive oxygen species (ROS) in living cells. The notion that the low intensity RFR can bring about significant oxidative
stress in living cells has been doubted for years. The logic is simple: as low intensity radiofrequency electromagnetic waves are not able to ionize molecules, they can do nothing wrong for the living tissues.

However, during the last decades a worldwide increase in penetration of wireless communication systems, including cellular telephony and Wi-Fi, attracted massive attention to possible biological effects of low

intensity RFR. Consequently, the recent epidemiological studies unexpectedly indicated a significant increase in the occurrence of various tumors among long-term and “heavy” users of cellular phones. These include brain tumors, acoustic neuromas, tumors of
parotid glands, seminomas, melanomas and lymphomas. Similarly, an increase in tumor incidence among people living nearby cellular base transmitting stations was also reported. As a result, in 2011 the World Health Organization/International Agency for Research on Cancer classified radiofrequency radiation as a possible carcinogen to humans.

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Source: Oxid Antioxid Med Sci 2014; 3(1):1-3, Yakymenko et al., 24 Mar 2014

Overproduction Of Free Radical Species In Embryonal Cells Exposed To Low Intensity Radiofrequency Radiation
Ukraine Created: 12 Dec 2013
Aim: Long-term exposure of humans to low intensity radiofrequency electromagnetic radiation (RF-EMR) leads to a statistically significant increase in tumor incidence - Mechanisms of such the effects are unclear, but features of oxidative stress in living cells under RF-EMR exposure were previously reported. Our study aims to assess a production of initial free radical species, which lead to oxidative stress in the cell.

Materials and Methods: Embryos of Japanese quails were exposed in ovo to extremely low intensity RF-EMR of GSM 900 MHz (0.25 μW/cm2) during 158–360 h discontinuously (48 c — ON, 12 c — OFF) before and in the initial stages of development. The levels of superoxide (O2·-), nitrogen oxide (NO·), thiobarbituric acid reactive substances (TBARS), 8-oxo-2’-deoxyguanosine (8-oxo-dG) and antioxidant enzymes’ activities were assessed in cells/tissues of 38-h, 5- and 10-day RF-EMR exposed and unexposed embryos.

Results: The exposure resulted in a significant persistent overproduction of superoxide and nitrogen oxide in embryo cells during all period of analyses. As a result, significantly increased levels of TBARS and 8-oxo-dG followed by significantly decreased levels of superoxide dismutase and catalase activities were developed in the exposed embryo cells.

Conclusion: Exposure of developing quail embryos to extremely low intensity RF-EMR of GSM 900 MHz during at least one hundred and fifty-eight hours leads to a significant overproduction of free radicals/reactive oxygen species and oxidative damage of DNA in embryo cells. These oxidative changes may lead to pathologies up to oncogenic transformation of cells.

A. Burlaka, O. Tsybulin, E. Sidorik, S. Lukin, V. Polishuk, S. Tsehmistrenko, I. Yakymenko
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of NAS of Ukraine, Vasylkivska str. 45, Kyiv 03022, Ukraine
Bila Tserkva National Agrarian University, Soborna pl. 8/1, Bila Tserkva 09117, Ukraine

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Source: Experimental Oncology, Burlaka et al., 12 Dec 2013

Long-term exposure to microwave radiation provokes cancer growth: evidences from radars and mobile communication systems
Ukraine Created: 27 Jul 2013
In this review we discuss alarming epidemiological and experimental data on possible carcinogenic effects of long term exposure to low intensity microwave (MW) radiation.

Recently, a number of reports revealed that under certain conditions the irradiation by low intensity MW can substantially induce cancer progression in humans and in animal models. The carcinogenic effect of MW irradiation is typically manifested after long term (up to 10 years and more) exposure. Nevertheless, even a year of operation of a powerful base transmitting station for mobile communication reportedly resulted in a dramatic increase of cancer incidence among population living nearby.

In addition, model studies in rodents unveiled a significant increase in carcinogenesis after 17-24 months of MW exposure both in tumor-prone and intact animals. To that, such metabolic changes, as overproduction of reactive oxygen species, 8-hydroxi-2-deoxyguanosine formation, or ornithine decarboxylase activation under exposure to low intensity MW confirm a stress impact of this factor on living cells.

We also address the issue of standards for assessment of biological effects of irradiation. It is now becoming increasingly evident that assessment of biological effects of non-ionizing radiation based on physical (thermal) approach used in recommendations of current regulatory bodies, including the International Commission on Non-Ionizing Radiation Protection (ICNIRP) Guidelines, requires urgent reevaluation.

We conclude that recent data strongly point to the need for re-elaboration of the current safety limits for non-ionizing radiation using recently obtained knowledge. We also emphasize that the everyday exposure of both occupational and general public to MW radiation should be regulated based on a precautionary principles which imply maximum restriction of excessive exposure.

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http://exp-oncology.com.ua/wp-content/uploads/2011/11/110.pdf
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Source: Pubmed, Yakymenko et al / via Paul Doyon, 27 Jul 2013

PACE calls on governments to ‘take all reasonable measures’ to reduce exposure to electromagnetic fields
Ukraine Created: 27 May 2011
The Parliamentary Assembly of the Council of Europe (PACE), meeting in Kyiv at Standing Committee level, today called on European governments to “take all reasonable measures” to reduce exposure to electromagnetic fields, especially to radio frequencies from mobile phones, “and particularly the exposure to children and young people who seem to be most at risk from head tumours”.

According to parliamentarians, governments should "for children in general, and particularly in schools and classrooms, give preference to wired Internet connections, and strictly regulate the use of mobile phones by schoolchildren on school premises”, and put in place information and awareness-raising campaigns on the risks of potentially harmful long-term biological effects on the environment and on human health, especially “targeting children, teenagers and young people of reproductive age”.

Following the proposals of the rapporteur (Jean Huss, Luxembourg, SOC), the Assembly called on governments to provide information on potential health risks of DECT-type wireless telephones, baby monitors and other domestic appliances which emit continuous pulse waves, if all electrical equipment is left permanently on standby. They should, instead, recommend “the use of wired, fixed telephones at home or, failing that, models which do not permanently emit pulse waves”.

Governments should “reconsider the scientific basis for the present electromagnetic fields exposure standards set by the International Commission on Non-Ionising Radiation Protection, “which have serious limitations” and apply as low as reasonably achievable (ALARA) principles.

The adopted resolution underlines the fact that “the precautionary principle should be applicable when scientific evaluation does not allow the risk to be determined with sufficient certainty” and stresses that “the issue of independence and credibility of scientific expertise is crucial” to achieve a transparent and balanced assessment of potential negative impacts on the environment and human health.

Adopted text:
http://assembly.coe.int/Mainf.asp?link=/Documents/AdoptedText/ta11/eRES1815.htm
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Source: Council of Europe Assembly, 27 May 2011

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